We develop and use bioinformatic tools for genomic analysis projects. The main projects are related to genome annotation, identification of long non-coding RNAs (lncRNAs), comparative genomics, NGS data analysis, directional selection study and evolution of canids.
We offer bioinformatic programs and web servers such :
- FEELnc : a program which annotate and classify lncRNAs [1]
- Autograph: a web server dedicated to comparative genomics [2]
- DoG_CNV: a database of variants of type Copy Number Variations[3]
- a study of dog loci that control phenotypic traits common or specific to dog breeds [4]
Detailed link: BIOINFORMATICS CANINE GENOMICS & GENETICS PROJECT
References :
[1] Wucher, V. et al. FEELnc: a tool for long non-coding RNA annotation and its application to the dog transcriptome. Nucleic Acids Res gkw1306 (2017). doi:10.1093/nar/gkw1306
[2] Derrien, T., André, C., Galibert, F. & Hitte, C. AutoGRAPH: an interactive web server for automating and visualizing comparative genome maps. Bioinformatics 23, 498–499 (2007).
[3] Berglund, J. et al. Novel origins of copy number variation in the dog genome. Genome Biol 13, R73 (2012).
[4] Vaysse, A. et al. Identification of genomic regions associated with phenotypic variation between dog breeds using selection mapping. PLoS Genet 7, e1002316 (2011).
